Lysine is an essential amino acid involved in many body functions. It intervenes in particular in the production of collagen , the formation of antibodies , carbohydrate metabolism and the absorption of calcium .
With many benefits for our body, lysine is mainly known for its effectiveness in the natural treatment of herpes virus infections . More details in this article!
What is herpes?
The term “herpes” is commonly used to refer to:
- Either a vesicular eruption in the labial region – also called a “cold sore” – due to the HSV 1 virus (Herpes simplex virus 1).
- Either a genital sexually transmitted disease (STD) due to the HSV 2 virus (Herpes simplex virus 2).

Herpes labialis or “cold sore” is a blistering rash (presence of small blisters containing fluid) appearing on a lip or other area around the mouth/nostrils.
It is a highly contagious viral infection that is transmitted through casual contact. It is estimated that between 60 and 90% of the general population carries the HSV 1 virus responsible for cold sores. The latter then manifests itself in a recurring manner, particularly during periods of stress or reduced immunity .
As for genital herpes , it is a sexually transmitted infection that manifests itself by itching , burning on the genitals caused by a blistering rash similar to that of cold sores.
Lysine against herpes: how effective?
Many scientific studies have investigated the benefits of lysine in the treatment of herpes infections . Here are the results of some of them:
Lysine decreases the frequency of cold sore outbreaks
The first studies on the use of lysine in the treatment of cold sores date from the 1980s, in particular with this double-blind clinical trial (1) conducted on a group of 65 people.

At the end of the trial, a decrease in the frequency of herpes outbreaks was demonstrated in the group treated with lysine (1000 mg daily) compared to the placebo group.
In other words, lysine could be used as a prophylactic treatment for cold sores (prevention of cold sores).
Lysine alleviates the symptoms of cold sores and accelerates its healing
Another study (2) (also double-blind) was performed in 46 patients to test the effects of lysine on herpes . Again, patients in the group treated with lysine (1000 mg 3 times a day for 6 months) had significantly fewer HSV infections compared to patients in the placebo group.
This study also showed a significant decrease in the severity of symptoms and a shortening of healing time .
In summary, based on the results of this study, taking lysine reduces the frequency of HSV infections , lessens their symptoms and speeds their healing .
Lysine can be used as an adjunct treatment for genital herpes
Lysine is also effective in the treatment of genital herpes (due to the HSV 2 virus), especially when used in the form of a cream for local application (directly on vesicular lesions in the genitals).
Nevertheless, it is essential to first consult your doctor to benefit from adequate care before considering any other treatment.
Lysine: how does it act against herpes?
According to research, lysine would be effective in the treatment of herpes infections because it prevents the multiplication of HSV viruses by blocking the action of arginine - knowing that arginine is an amino acid essential for growth and reproduction of these viruses.
Indeed, it has been observed that when lysine levels in the body exceed those of arginine , HSV viruses stop multiplying and herpes symptoms disappear more quickly .

Lysine against herpes: precaution to take
When taking a food supplement based on lysine in order to prevent or treat herpes labialis, it is important to avoid the consumption of foods rich in arginine (chocolate, nuts, seeds, peanuts, etc.), because this could reduce the effectiveness of lysine .
Conclusion
Lysine supplementation contributes to the prevention of herpes outbreaks , as well as to the alleviation of their symptoms and the acceleration of their healing .