{"product_id":"vitamine-b9-nutripure","title":"Vitamine B9 Quatrefolic® Nutripure","description":"\u003ch2\u003eVitamin B9 (folate): the key nutrient for pregnancy and energy\u003c\/h2\u003e\n\u003cp\u003eVitamin B9 — also known as folate or folic acid depending on its form — is one of the few vitamins for which official supplementation guidance has been issued by health authorities, particularly for all women planning a pregnancy. Water-soluble by nature, it is not stored long-term by the body: a regular intake is essential to meet daily needs.\u003c\/p\u003e\n\u003cp\u003eIts scope of action is broad and officially recognised at European level: vitamin B9 contributes to maternal tissue growth during pregnancy, to the reduction of tiredness and fatigue, to normal blood formation, to normal psychological function, and to the normal functioning of the immune system.\u003c\/p\u003e\n\u003ch2\u003eWhat is vitamin B9 and what does it do?\u003c\/h2\u003e\n\u003cp\u003eFolates work at the heart of cellular machinery: they are essential for DNA synthesis and play a central role in the process of cell division. In practice, every time your body makes new cells — red blood cells, immune cells, growing tissues — vitamin B9 is called into action.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnancy and motherhood\u003c\/strong\u003e: it contributes to the growth of maternal tissues during pregnancy, a time when cell division accelerates considerably.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergy and vitality\u003c\/strong\u003e: by taking part in normal blood formation — and therefore in oxygen transport — it contributes to reducing tiredness and fatigue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMental balance\u003c\/strong\u003e: it contributes to normal psychological function.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunity\u003c\/strong\u003e: it supports the normal functioning of the immune system.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolism\u003c\/strong\u003e: it contributes to normal homocysteine metabolism and to normal amino acid synthesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy supplement with vitamin B9?\u003c\/h2\u003e\n\u003cp\u003eFolates are found in leafy green vegetables, legumes, eggs and liver — but they are fragile molecules: a significant portion is destroyed by cooking, light and storage. The result is that even with a careful diet, reaching an optimal folate status is difficult, and the \u003ca href=\"https:\/\/efsa.onlinelibrary.wiley.com\/doi\/10.2903\/j.efsa.2014.3893\" rel=\"noopener\" target=\"_blank\"\u003eEFSA opinion on dietary reference values\u003c\/a\u003e sets considerably higher requirements for pregnant women (600 µg of folate equivalents per day, compared with 330 µg for adults).\u003c\/p\u003e\n\u003cp\u003eThree situations make supplementation particularly relevant:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePlanning a pregnancy and the first trimester\u003c\/strong\u003e, when needs increase sharply (see below).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTemporary tiredness\u003c\/strong\u003e, as an insufficient folate status can translate into lower energy levels linked to less efficient blood formation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiets low in folates\u003c\/strong\u003e: few green vegetables, prolonged cooking, periods of intense activity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVitamin B9 and pregnancy: why start before conception?\u003c\/h2\u003e\n\u003cp\u003eThis is the defining use case for vitamin B9. The neural tube of the developing baby — the precursor to its brain and spinal cord — closes between day 21 and day 28 of pregnancy, often before the pregnancy is even known. This is why health authorities recommend starting supplementation from the moment a pregnancy is planned, at least one month before conception, and continuing throughout the first trimester.\u003c\/p\u003e\n\u003cp\u003eThe European-validated claim is precise: \u003ca href=\"https:\/\/efsa.onlinelibrary.wiley.com\/doi\/10.2903\/j.efsa.2013.3328\" rel=\"noopener\" target=\"_blank\"\u003esupplemental folate intake increases maternal folate status; a low maternal folate status is a risk factor in the development of neural tube defects in the developing foetus\u003c\/a\u003e. The beneficial effect is obtained with a supplemental intake of 400 µg per day for at least one month before conception and up to three months after — exactly the dose in one capsule of our formula.\u003c\/p\u003e\n\u003ch2\u003eAn active form, suitable for everyone\u003c\/h2\u003e\n\u003cp\u003eNot all forms of vitamin B9 are equal. Standard synthetic folic acid must go through several enzymatic conversion steps before becoming the active circulating form, 5-methyltetrahydrofolate (5-MTHF). The key enzyme in this chain, MTHFR, exists in genetic variants that are less efficient: depending on the population, \u003ca href=\"https:\/\/doi.org\/10.3109\/00498254.2013.845705\" rel=\"noopener\" target=\"_blank\"\u003ea significant proportion of individuals convert folic acid poorly\u003c\/a\u003e, which can limit the body's actual use of the vitamin and leave unmetabolised folic acid circulating in the blood.\u003c\/p\u003e\n\u003cp\u003eThis 4th-generation vitamin B9 is delivered directly as 5-MTHF, the already-active form: it requires no conversion and is ready for the body to use regardless of genetic profile. Research has also evaluated \u003ca href=\"https:\/\/doi.org\/10.1515\/jpm-2012-0256\" rel=\"noopener\" target=\"_blank\"\u003e5-MTHF as an alternative to folic acid\u003c\/a\u003e, with the advantage of not generating unmetabolised folic acid in the blood.\u003c\/p\u003e\n\u003ch2\u003eWhy choose our vitamin B9?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e 5-MTHF Quatrefolic®\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhysiological dose of 400 µg per capsule\u003c\/strong\u003e: the reference dose recommended for pre-conception use, with no unnecessary excess.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eJust one capsule a day\u003c\/strong\u003e: easy to stick to — essential for a vitamin the body does not store.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClean formula\u003c\/strong\u003e: vegetable capsule (pullulan), free from titanium dioxide, magnesium stearate, and controversial additives.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow to recognise an insufficient folate intake?\u003c\/h2\u003e\n\u003cp\u003eA low vitamin B9 status builds up quietly. The most common signs are non-specific: persistent tiredness, unusual breathlessness during effort, pallor, irritability or difficulty concentrating. These signs can be explained by the role folates play in red blood cell formation: a prolonged shortfall can affect how well oxygen reaches the body's tissues. If these signs persist, speak to your doctor — a blood folate test can give a clear picture of the situation.\u003c\/p\u003e\n\u003cp\u003eWorth noting: vitamin B9 works in close partnership with vitamin B12, both contributing to normal blood formation. If fatigue is ongoing, checking the status of both is a sensible step.\u003c\/p\u003e\n\u003ch2\u003eHow to take vitamin B9?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage\u003c\/strong\u003e: 1 capsule per day with a glass of water, preferably in the morning.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePlanning a pregnancy\u003c\/strong\u003e: start at least 1 month before conception and continue for at least the entire first trimester, in consultation with your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTemporary tiredness\u003c\/strong\u003e: a 3-month course, renewable as needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eScientific references\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEFSA NDA Panel (2014). Scientific Opinion on Dietary Reference Values for folate. \u003cem\u003eEFSA Journal\u003c\/em\u003e, 12(11):3893. \u003ca href=\"https:\/\/efsa.onlinelibrary.wiley.com\/doi\/10.2903\/j.efsa.2014.3893\" rel=\"noopener\" target=\"_blank\"\u003eView the opinion\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eEFSA NDA Panel (2013). Scientific Opinion on the substantiation of a health claim related to increasing maternal folate status by supplemental folate intake and reduced risk of neural tube defects. \u003cem\u003eEFSA Journal\u003c\/em\u003e, 11(7):3328. \u003ca href=\"https:\/\/efsa.onlinelibrary.wiley.com\/doi\/10.2903\/j.efsa.2013.3328\" rel=\"noopener\" target=\"_blank\"\u003eView the opinion\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eScaglione F, Panzavolta G (2014). Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. \u003cem\u003eXenobiotica\u003c\/em\u003e, 44(5), 480-488. \u003ca href=\"https:\/\/doi.org\/10.3109\/00498254.2013.845705\" rel=\"noopener\" target=\"_blank\"\u003eView the study\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eObeid R, Holzgreve W, Pietrzik K (2013). Is 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects? \u003cem\u003eJournal of Perinatal Medicine\u003c\/em\u003e, 41(5), 469-483. \u003ca href=\"https:\/\/doi.org\/10.1515\/jpm-2012-0256\" rel=\"noopener\" target=\"_blank\"\u003eView the study\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProFeel Life","offers":[{"title":"1-PACK","offer_id":55642239762808,"sku":null,"price":19.9,"currency_code":"CHF","in_stock":true},{"title":"2-PACK","offer_id":55642780696952,"sku":null,"price":37.8,"currency_code":"CHF","in_stock":true},{"title":"4-PACK","offer_id":55642782531960,"sku":null,"price":71.65,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0611\/1212\/3637\/files\/VitamineB9gelulesnutripure.jpg?v=1787839838","url":"https:\/\/profeel.life\/en\/products\/vitamine-b9-nutripure","provider":"ProFeel Life","version":"1.0","type":"link"}