In the vast world of dietary supplementsthe Myo-Inositol stands out as a precious ally for our well-being! 🌟 Supported by numerous scientific studiesit is particularly effective for people suffering from diabetesdiabetes PCOS (polycystic ovary syndrome) and fertility disorders. In five years, consumption of this molecule as a dietary supplement has increased by by over 40%! 📈
Visit myo-inositol offers a multitude of benefitsranging from hormonal regulation to improving mental health 🧠. Read on to find out all about this natural compound!
What is myo-inositol?
The myo-inositol is a form of the inositol molecule molecule, often referred to as vitamin B7, although it is not strictly speaking a vitamin.
This molecule, present in many of the foods we consume every day, such as cereals wholegrain cereals 🌽cereals nuts 🌰 and legumes 🫘, plays an essential role in the cell metabolismmetabolism, particularly in regulation of blood sugar by insulin and the the functioning of our cell membranes [1].
One of the outstanding benefits of myo-inositol concerns the polycystic ovary syndrome (PCOS). In the following sections, we'll take you through some of the many studies that have highlighted the beneficial effects of this natural molecule on women suffering from PCOSincludingfertility improvement and insulin regulation.
Myo-inositol is also involved in the production of neurotransmitters such as serotoninthus playing a crucial role in the proper functioning of the nervous system 🧠.
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By supporting the production of serotonin, the neurotransmitter of happiness, the myo-inositol supplementation helps reduce anxiety and improve mood 🌟
What are the benefits and properties of inositol?
Visit myo-inositolis often affiliated with the vitamin family, in this case the group B vitaminsgroup, is a molecule with many benefits and properties. The intake of inositol-rich supplement is recognized for its beneficial effects on several aspects of health, including :
The benefits of inositol on PCOS
The polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting women of childbearing age. It is characterized by imbalance hormonal imbalancean ovulation irregular (deregulated menstrual cycle) and formation of small cysts on the ovaries.
Taking dietary supplements containing myo-inositol has shown significant benefits for women of childbearing age suffering from polycystic ovary syndrome or "PCOS".
In fact, many women return to regular cycles after just a few weeks. 3 months of inositol supplementationsupplementation, thus reducing PCOS symptoms. This molecule has even been dubbed the "fertility molecule» 💊 for its remarkable effects.
Here's how myo-inositol works for reduce PCOS symptoms [2], [3] :
Improves insulin sensitivity
One of the main problems encountered by women with PCOS is the insulin resistance. This resistance leads to high insulin levels, which in turn cause excessive production of insulin. of androgens (male sex hormones).
Myo-inositol helps to increase cell sensitivity to insulin 🩸, thereby reducing levels of this hormone and, consequently, androgen production.
It regulates ovarian function
In healthy women (between puberty and menopause), the menstrual cycle is regular and lasts an average of 28 days (the interval between two menstrual periods). On the other hand, women suffering from PCOSthe cycle is disrupted, irregular.
By reducing high levels of androgens, the myo-inositol may help regulate the menstrual cycle.
Improves oocyte quality
The "oocytes"are the female sex cellscells, those destined to fuse with the spermatozoon (fertilization) to produce a embryo (future baby!).
Many women experience difficulties getting pregnant🤰 due to poor oocyte quality. They must then consult a doctor👨⚕️, preferably a specialist in fertility disorders, to benefit from appropriate medical management aimed at increasing their chances of conceiving.
According to research myo-inositol plays a key role in oocyte maturation. Improved oocyte quality is essential for fertility, and many women with PCOS resort to myo-inositol supplementation 🌿 when trying to conceive.
Reduces signs of hyperandrogenism
Excess androgens in women with PCOS can lead to symptoms such as acneand excessive hair growth (hirsutism) and hair loss. By helping to balance hormone levels, the myo-inositol can help reduce these symptoms.
The metabolic properties of myo-inositol
Visit myo-inositolderived from sugar (glucose), plays a vital role in the lipid metabolism. When taken as a dietary supplement, it has a beneficial effect on weight in obese people, by improving the metabolism of lipids. metabolism metabolism.
Here are some of the main benefits of myo-inositol on metabolism:
- Improves insulin sensitivity myo-inositol helps cells to respond more effectively to insulin, which is particularly beneficial for people with resistance to this hormone, such as those with PCOS or type 2 diabetes 🩸 [2], [3].
- Regulates lipid metabolism myo-inositol influences fat metabolism, notably by helping to reduce triglyceride and cholesterol levels in the blood, thus promoting a healthy lipid profile 🧈 [4].
- It plays a role in neuronal function myo inositol appears to be involved in the formation and release of certain neurotransmitters, such as serotonin, thus playing an important role in mood and sleep 🧠😴.
- Regulates intracellular calcium concentration myo-inositol is involved in the regulation of calcium within our cells, since calcium is an essential element in many cellular metabolism reactions 🔁.
- Helps detoxify the liver some evidence suggests that myo-inositol may have beneficial effects on liver function, notably by helping to eliminate excess fat from the liver 🍃.
So it's clear that myo-inositol exerts a profound influence on human metabolism.
The benefits of myo-inositol on fertility
Visit myo-inositol plays an important role in the regulation of several biological processes essential for the fertilityin both men and women. 🌿
Its beneficial effects are mainly linked to its role in the oocyte quality and hormonal regulation..
Here are the main effects of myo-inositol on fertility:
In women:
- Improves oocyte quality 🥚
- Regulates menstrual cycle 🩸
- Reduces insulin resistance 💉
- Reduces oxidative stress which damages oocytes 🌟
For men:
- Improves sperm parameters (sperm mobility and morphology) 🧬
- Protects spermatozoa from oxidative stress 🛡️🌟
- Improves insulin sensitivity and helps balance levels androgen levels (male hormones essential for fertility and sexual health) ⚖️
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The beneficial effects of myo-inositol on the oocyte and sperm quality make it a valuable asset for couples wishing to conceive.
Other benefits of myo-inositol
In addition to its effects on fertility and metabolism, myo-inositol offers a host of other health benefits:
- Mental health myo-inositol may help reduce symptoms of depressionsymptoms panic disorder and obsessive-compulsive disorder 🧠.
- Gestation and pregnancy myo-inositol supplementation could reduce the risk of gestational diabetes and help avoid the need for insulin in some pregnant women 🤰.
- Neuroprotection Preliminary studies suggest that myo-inositol may play a role in neuroprotection. neuroprotective rolealthough further research is required 🛡️.
- Function thyroid function in combination with nutrients such as seleniummyo-inositol can support the proper functioning of the immune system. thyroid function and modulate certain autoimmune thyroid conditions 🦋.
- Oxidative stress helps reduce oxidative stressoxidative stress, offering protection against premature ageing 🌟.
- Cellular health Cellular health: as a component of phospholipids, myo-inositol plays a crucial role in structure and of cell membranes 🧬.
In addition, a American study published in 2023 revealed a crucial role for myo-inositol in the development and neuronal connectivity 🧠. This component, naturally present in breast milk, has been shown to be beneficial for the development of synapses in various species, including humans.
These findings suggest that myo-inositol may play a key role not only in the nutrition nutritionbut also in improving infant formulasespecially in disadvantaged regions where breastfeeding may be insufficient.
In addition, this compound could also promote synapse density in mature brain tissue. Its potential to improve brain health at every stage of life never ceases to amaze us!
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Visit myo-inositol is often used as a dietary supplement to support not only the metabolism, but also the metabolism. health mental health and fertility. 🌿 It's a versatile ally for improving your overall well-being!
What is the recommended dosage of myo-inositol?
The recommended dosage of myo-inositol varies according to the indication for which it is to be used.
Here are the commonly recommended dosages, based on clinical studies and expert advice:
- Polycystic ovary syndrome (PCOS) 🩸 : 2,000 mg to 4,000 mg (2-4 grams) per day.
- Fertility 👶 To improve oocyte quality and other aspects of fertility, a dosage of 2,000 mg to 4,000 mg per day is often recommended.
- Mood disorders 🧠 for conditions such as depression or anxiety, higher dosages ranging from 12,000 mg to 18,000 mg (12-18 grams) per day have been studied.
- Metabolic disorders 🩸: to improve insulin sensitivity and other metabolic parameters, 2,000 mg to 4,000 mg per day are generally recommended.
- Autism spectrum disorders 🧬: dosages of up to 18,000 mg (18 grams) per day have been studied, although further research is needed to confirm their safety and efficacy in this population.
Warning
Strictly observe the dosages indicated on food supplements, and consult a healthcare professional if in doubt.
What are the side effects of myo inositol?
The myo-inositol is generally well tolerated when taken in recommended doses. However, as with all supplementsome side effects may occur in certain individuals:
- Gastrointestinal disorders 🤢: nausea, gas, bloating, diarrhea, abdominal pain.
- Dizziness and headaches 🤕: dizziness, headaches.
- Unexplained fatigue 😴 Feeling tired for no apparent reason.
- Risk of hyponatremia 🌡️: reduced sodium levels in the blood, which can be dangerous.
- Allergic reactions 🚨 : risk of allergic reactions with rash, itching, swelling or breathing difficulties.
Conclusion
The myo-inositolalthough associated with B vitaminsis much more than a simple supplement. This versatile molecule offers numerous benefitsparticularly for people suffering from PCOSproblems fertilityand certain disorders metabolic disorders 🌿.
The studies also show that myo-inositol can play an important role in the regulation of insulin sensitivitysensitivity thyroid healthand mental well-being 🧠.
If you're looking to improve your overall well-being, whether for support your fertility, balance your metabolism or promote good mental healthare considering joining our myo-inositol-based supplement into your routine!
FAQ
What is myo-inositol and where can I find it?
Myo-inositol is a form of the inositol molecule, sometimes called vitamin B7, although it is not technically a vitamin. It is found naturally in whole grains, nuts and legumes. It plays a crucial role in cellular metabolism, blood sugar regulation and cell membrane function.
How does myo-inositol improve the symptoms of polycystic ovary syndrome (PCOS)?
Myo-inositol helps increase cell sensitivity to insulin, thereby reducing high levels of this hormone and, consequently, androgen production. This can help regulate ovarian function and the menstrual cycle, improve oocyte quality, and reduce signs of hyperandrogenism such as acne and excess body hair.
What are the fertility benefits of myo-inositol?
In women, myo-inositol improves oocyte quality and regulates the menstrual cycle. In men, it improves sperm mobility and morphology and protects against oxidative stress. This makes it a valuable supplement for couples trying to conceive.
What are the possible side effects of taking myo-inositol?
Myo-inositol is generally very well tolerated, especially when the manufacturer's instructions are followed. Minor side effects may occasionally occur, such as mild gastrointestinal upset or fatigue, but these are rare and often related to inappropriate dosage.
References
- "Inositol: the great communicator".
- V. Unfer, F. Facchinetti, B. Orrù, B. Giordani, and J. Nestler, "Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials", Endocr. Connect. vol. 6, no. 8, pp. 647-658, Sept. 2017, doi: 10.1530/EC-17-0243.
- R. D'Anna et al, "Myo-inositol may prevent gestational diabetes in PCOS women," Gynecol. Endocrinol, vol. 28, no. 6, pp. 440-442, June 2012, doi: 10.3109/09513590.2011.633665.
- R. Tabrizi et al, "The effects of inositol supplementation on lipid profiles among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials," Lipids Health Dis, vol. 17, no. 1, p. 123, May 2018, doi: 10.1186/s12944-018-0779-4.
- R. Gambioli, G. Forte, G. Buzzaccarini, V. Unfer, and A. S. Laganà, "Myo-Inositol as a Key Supporter of Fertility and Physiological Gestation", Pharmaceuticals, vol. 14, no. 6, Art. no. 6, June 2021, doi: 10.3390/ph14060504.
- W.-D. Jiang et al, "Myo-inositol prevents copper-induced oxidative damage and changes in antioxidant capacity in various organs and the enterocytes of juvenile Jian carp (Cyprinus carpio var. Jian)", Aquat. Toxicol, vol. 105, no. 3, pp. 543-551, Oct. 2011, doi: 10.1016/j.aquatox.2011.08.012.
- M. h. Vazquez-Levin and G. l. Verón, "Myo-inositol in health and disease: its impact on semen parameters and male fertility", Andrology, vol. 8, no. 2, pp. 277-298, 2020, doi: 10.1111/andr.12718.
- M. Montanino Oliva, R. Poverini, R. Lisi, M. C. Carra, and F. Lisi, "Treating Woman with Myo-Inositol Vaginal Suppositories Improves Partner's Sperm Motility and Fertility," Int. J. Endocrinol, vol. 2016, p. e7621942, June 2016, doi: 10.1155/2016/7621942.
- R. Ponchia et al, "Oxidative Stress Measurement in Frozen/Thawed Human Sperm: The Protective Role of an In Vitro Treatment with Myo-Inositol," Antioxidants, vol. 11, no. 1, Art. no. 1, Jan. 2022, doi: 10.3390/antiox11010010.
- S. Benvenga and A. Antonelli, "Inositol(s) in thyroid function, growth and autoimmunity", Rev. Endocr. Metab. Disord. vol. 17, no. 4, pp. 471-484, Dec. 2016, doi: 10.1007/s11154-016-9370-3.
- S. Benvenga et al, "Protective Effects of Myo-Inositol and Selenium on Cadmium-Induced Thyroid Toxicity in Mice," Nutrients, vol. 12, no. 5, Art. no. 5, May 2020, doi: 10.3390/nu12051222.
- "Role of selenium and myo-inositol supplementation on autoimmune thyroiditis progression". Accessed: September 30, 2023. [Online]. Available at: https://www.jstage.jst.go.jp/article/endocrj/67/11/67_EJ20-0062/_article/-char/ja/
- S. Benvenga, M. Nordio, A. S. Laganà, and V. Unfer, "The Role of Inositol in Thyroid Physiology and in Subclinical Hypothyroidism Management," Front. Endocrinol, vol. 12, 2021, Accessed: September 26, 2023.
